Dr.Amrit Kaur Kaler - Best Molecular Pathologist in Mumbai

Dr. Amrit Kaur Kaler

Consultant, Molecular Pathology

MBBS, MD. (Pathology); Fellowship in Molecular Biology and Genomics (HCG Cancer care);Certificate Course in Cancer Genomics and Precision Oncology, Immuno-oncology (Harvard Medical School).

  • YEARS OF PRACTICE: 15 Years
  • GENDER: Female
  • LANGUAGES SPOKEN: English, Hindi, Punjabi
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Biography

Dr (Prof) Kaler is Molecular Pathologist, trained in clinical genomics testing of solid tumors and Hematological Malignancies. One of her current interestareas is connecting morpho-genomics to precision oncology. Her top research area is immunotherapy along with new targeted therapy which might change the course of cancer in future. She is skilled in handling laboratory operations across department of histopathology, hematology and clinical pathology.She has more than 45 papers in National and International journals and Co-author of post graduate Pathology book. She is recipient of multiple awards in area of Pathology and Leadership.She is also a regular speaker in medical conferences and seminars. She is very passionate about women empowerment and helping women in rural India.

My Mantra

Productive, creative and bring a positive change in every soul I meet

AREA(S) OF INTEREST:

Cancer genomics, Molecular Pathology, Solid Tumors, Hematological Malignancies, Precision Oncology, Immunooncology, Hereditary Cancers

PROCEDURES PERFORMED:

Next Generation Sequencing, Polymerase Chain reaction, Sanger Sequencing, MLPA

TREATMENTS/PROCEDURES OFFERED:

  • Breast cancers
  • colorectal malignancies, lung cancers, melanomas, ovarian cancers, pancreatic cancers, haematological malignancies, neurological disorders

NAME OF INSTITUTE(S):

    • Government Medical College, Amritsar
    • Dr B. R. Ambedkar Medical College, Bangalore
    • St. Johns Medical college and Hospital, Bangalore
    • Healthcare Global Cancer Care Hospital, Bangalore
    • Harvard Medical School, Boston, USA

FELLOWSHIPS:

    Fellowship in Molecular Biology and Genomics

Recognitions

  • Co-authored A Book: Principles And Interpretation Of Laboratory Practices In Surgical Pathology- Edition 1
    This book is recommended for all the practicing pathologists, anatomists, microbiologists and forensic medicine to refer for various diagnostic procedures. It also covers routine and special staining procedures used in histopathology, anatomy and microbiology laboratories and is comprehensive with outlines of principles, methodology and troubleshooting. It also provides recent advances in methodology, molecular techniques, biomedical disposal and safety measures. It also outlines quality control in laboratories, audit and quality assurance programmers.
  • South Asian Editor –Washington Manual of Surgical Pathology -3E Paperback
    ISBN-13 978-9390612499;
    Publisher Wolters Kluwer India Pvt ltd
    Edition SAE
    Publication Date 5 August 2022

Awards

  • Received the “Best Paper Award” at a national conference on paper entitled “Spectrum of Hemoglobinopathies in the Sikh community of Bangalore” in KC-IAPM, 2012 at NIMHNAS convention hall, organized by Bangalore Medical College, Bangalore.
  • Received the “INDIAN WOMEN ACHIEVER AWARD” by the National Institute for Education Research (NIER), India, in 2015.
  • Excellence in research by Indus foundation on Thalassemia in February 2017.
  • Received the “GAURAVACHARYA” Award by the National Institute for Education Research (NIER), India, in 2016.
  • Received the “Best Molecular Pathologist” in Mumbai award at the National Leadership Awards by Devoxil Media in 2022.
  • Participated in the International Symposium on Precision Oncology and Personalised Medicine held on 30th April 2023 at Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute Mumbai.
  • Awarded with “Certificate of Excellence” for its contribution in Research and Academics by Health Care Global, Bangalore, 2024.
  • Awarded with “Best Research paper” on the occasion of Research day celebration by Kokilaben Hospitals, Mumbai in Nov 2024.
  • Honoured with “Associate Board Member” by Genetic Counselling Board of India, 2025
  • Awarded With “Cerificate of Advanced Studies in precision Medicine” by International Society of Liquid Biopsy, February, 2025
  • Awarded with “Molecular Pathologist of the year” at the Precision Med India Conclave by Voice of Healthcare (VOH) and NEXT EDGE on 20th April 2025.

KDAH Experience

Dr (Prof) Amrit Kaler heads the Molecular Pathology Department and is responsible for the reporting molecular and cancer genetic panels.

  • Kaler Amrit Kaur; Upadhyay Shraddha Manoj; Satpute Shalaka; Nagpal Shachi Deepak; Chaudhary Vaibhav. Complete Response to Sequential Peptide Receptor Radionuclide Therapy and Sunitinib in SDHB-mutated Metastatic Paraganglioma. Journal of Precision Oncology :10.4103/jpo.jpo_5_25, September 05, 2025.
  • Kaler Amrit, Jethani Manish, Nadkarni Mandar, Tiwarekar Yash, Balaji Varsha, Wairkar Tanmay, Kulkarni Bijal, Athikari Nevitha, Satpute Shalaka, Agarwal Ratika, Kumar Shruthi, Shah Vidhi, Goyle Sandeep, Shaikh Imran,Mistry Rajesh. (2025). Molecular Subtyping and Classification of PIK3CA Mutations in Metastatic Breast Cancer. Current Tissue Microenvironment Reports. 1-10.
  • Kaur, K., Manoj, U., Shyamali, B., Ankita, N., Kavya, P., Nivetha, A., B, S., Imran, S., & Rajesh, M. (2024). Germline BRCA1 Mutation in Squamous Cell Carcinoma of Oesophagus: Driver versus Passenger Mutation. Journal of Genetic Medicine and Gene Therapy. https://doi.org/10.29328/journal.jgmgt.1001011.
  • Kaler, Amrit, Fatima Sheereen, Dhurat Omkar,Rane Samrudhi, Limaye Shweta,Umarji Smitha, Tiwarekar Yash, Nikam Ankita, Kulkarni Bijal, Athikari Nevitha, Shaikh Imran, Goyle Sandeep, Mulchandani Manoj, Kulkarni Yogesh, Mistry Rajesh. (2024). Role of Microsatellite Instability as Pan-Cancer Agnostic Marker of Solid Tumours in Personalized Medicine. Current Tissue Microenvironment Reports. 5. 1-9. 10.1007/s43152-024-00054-5.
  • Kaler Amrit, Shyamali Bora, Upadhyay Shraddha Manoj, Shalaka Satpule, Ankita Nikam, Yash Tiwarekar, Mandar Deshpande. (2024). Unlocking the Potential of Multigene Parallel Sequencing: A Concomitant Germline RET and BRCA1 Mutation in a Hereditary Medullary Thyroid Carcinoma. Archives of Case Reports. 8. 126-130. 10.29328/journal.acr.1001111.
  • Fatima Sheereen, Shaikh Imran, Mistry Rajesh, Kaler Amrit. (2023). Long-term efficacy of osimertinib in de novo exon 19 deletion with T790M in an epidermal growth factor receptor mutated lung cancer patient in India. International Journal of Molecular and Immuno Oncology. 9. 1-4. 10.25259/IJMIO_16_2023.
  • Kaler AK, Bora NS, Kavyashree P, Nikam A, Rane S, Tiwarekar Y, et al. Mini review: Molecular pathology of personalized medicine in cancer susceptibility syndromes. Int J Mol Immuno Oncol 2023;8:81-8.
  • Fatima, Sheereen; Kaler, Amrit Kaur; Shaikh, Imran Nisar. Genomically Driven NUTM1-NSD3 Carcinoma of the Lung: Opportunity for Chemotherapy Response. Journal of Precision Oncology 3(1): p 54-57, Jan–Jun 2023. | DOI: 10.4103/jpo.jpo_9_23]
  • Kaler, Amrit; Maskomani, Silambarasan, Ritambhara, Kavyashree, Vadera, Varsha ,Choudhary, Vaibhav, Shaikh, Imran, Goyle Sandeep, Mistry, Rajesh. (2023). Evolution of Biomarkers and Treatment Outcomes of Immunotherapy in Lung Cancer. Current Tissue Microenvironment Reports. 4. 1-23. 10.1007/s43152-023-00047-w.
  • Kaler, Amrit Kaur; Fatima, Sheereen; Bora, Nandini Shyamali; Satpute, Shalaka; Balaji, Varsha; et l. Prognostic Impact of Lynch Syndrome in Signet-Ring Cell Carcinoma: A Case Report and Review. Journal of Precision Oncology 3(1): p 49-53, Jan–Jun 2023.
  • Kaler AK, Dharut O, Umarji S, Limaye S, Kulkarni B, et al. Molecular Diversity and Characteristics of KRAS Mutations in Colorectal Cancers. 2023 Jan 24; 4(1): 077-083. doi: 10.37871/jbres1650, Article ID: jbres1650
  • Kaler AK, Patel K, Patil H, Tiwarekar Y, Kulkarni B, et al. Mutational Analysis of EGFR Mutations in Non-Small Cell Lung Carcinoma-An Indian Perspective of 212 Patients. Int J Environ Res Public Health. 2022 Dec 31;20(1):758. doi: 10.3390/ijerph20010758. PMID: 36613084; PMCID: PMC9819110.
  • Fatima, Sheereen, Imran Nisar Shaikh, and Amrit Kaur Kaler. "CHEK2 gene in metastatic prostate cancer: A cordial check on DNA damage repair pathway." International Journal of Molecular and Immuno Oncology 8.1 (2023): 31-34.
  • Amrit Kaur Kaler, Dhruvin Boricha, Smitha Umarji, Yash Tiwarekar, Samrudhi Rane, et al. Pleiotropic Manifestation of Pathogenic ACTB Gene in Baraitser-Winter Syndrome. Biomed J Sci & Tech Res 48(2)-2023. BJSTR. MS.ID.007612.
  • Kaler AK, Rabade N, Ghodke K, Tiwarekar Y, Umarji S, et al. Acute myeloid leukemia with nucleophosmin 1 mutation: Clonal hematopoiesis with indeterminate potential or oncogenic potential?. J Precis Oncol 2022;2:143-5
  • Kaler, Amrit Kaur, et al. "Molecular profiling of large B-Cell lymphomas: A retrospective observational pilot study." Journal of Precision Oncology 2.2 (2022): 125.
  • Kaler AK, Vishal Rao U S. The role of the pathologist in the next-generation era of molecular oncology. J Precis Oncol 2022;2:52-3
  • Kaler AK, Thomas R, Suhas NG, Prarthana VK, Dharman B, et al. An experience of Methylguanine-DNA methylation assay (MGMT) characterization in Glial tumors with methylation assay. J of Precis Oncol 2022;2:9-13.
  • Kaler AK. Gross Picturesque: Case of the journal. J Precis Oncol 2022;2:54-5.
  • Kaler AK, Gaur R, Jain A, Rajan J, Vishal Rao U S. Detection of antinuclear antibodies in oncology from slide to multiplexing: An overview. J Precis Oncol 2022;2:36-9
  • Kaler AK, Rao M S, Roopamouli M, Srinivasalu Y, Narasimha Raju SL, Vishal Rao U S. Cost-effectiveness of cervical cancer screening in rural Bengaluru with demographic analysis of epithelial cell abnormalities: A cross-sectional descriptive study. J Precis Oncol 2022;2:14-8.
  • Kaler, A. K., & Balaram, G. (2021). Triple negative breast Cancer classification from morphology to genomics. American Journal of Translational Medicine, 5(3), 138-146.
  • Amrit Kaur Kaler, Meenu E V, Chandrakant PN, Patil C. A Clinical Dilemma in the Diagnosis of Primary Synovial Osteochondromatosis of Knee. Sch. J. Med. Case Rep., Aug 2018; 6(8): 495-499
  • Amrit Kaur Kaler, Uma Bai KR, Chandra Shekhar P, Vishwanathan. Spectrum of Hemoglobinopathies in The Sikh community of Bangalore: A pilot study. IP Journal of Diagnostic Pathology and Oncology 2018; 3 (2). Print-Issn: 2581-3714.
  • Amrit Kaur Kaler, Kunal Sharma. SAT B2 a novel diagnostic adjunct in a rare presentation of extra skeletal osteosarcoma of scrotum. IP Journal of Diagnostic Pathology and Oncology 5(4):430-433
  • Dr. Divya Lakshmi, Dr. Amrit Kaur Kaler, Dr. Rashmi V. Fibroadenoma in ectopic breast tissue: A series of 3 cases. Paripex-Indian Journal of Research 2018; 7(4).
  • Amrit Kaur Kaler, K Shweta, Smitha Chandra B.C, Naik S. Spindle Cell Carcinoma of the Tongue: Fallacies in Its Diagnosis. International Journal of Innovative Research in Medical Science 2018; 3 (2). ISSN No. - 2455-8737.
  • Amrit Kaur Kaler, Naveen Kumar BJ. Angiolymphoid Hyperplasia with Eosinophilia Developing in a 9-Year-Old Patient with History of Tuberculosis. International Journal of Innovative Research in Medical Science (IJIRMS). 2017; 02(11).
  • Kaler AK, Manjunath YA, Varaprasad BM. Collagenous spherules of the breast: A diagnostic enigma. J. Evid. Based Med. Healthc. 2016; 3(36), 1795-1797. DOI: 10.18410/jebmh/2016/401
  • Raja Parthiban, Amrit Kaur Kaler, M. Sangeeta, Suresh Hanagavadi, P. Sashikala, Shameem Shariff. A Clinico-Pathological Study of Hemophilia in Rural Set up of Karnataka. British Journal of Medicine and Medical Research, ISSN: 2231-0614. 2014; 6: 10.  
  • Kaler AK, Parthiban R, Gandhi N, HT Jayaparkash. Thyroid FNAC: Experience with Thyroid Bethesda system in practice. National Journal of Basic Medical Sciences, 4 (1); July-September 2013.
  • Kaler AK, Viswanath Veeranna, Uma Bai, Raja P, Parminder Kaur. Role of HPLC in the diagnosis of Hemoglobin Q Disease. IJHSR. 2013; 3(8): 96-99.
  • Kaler AK, Parthiban R, Gandhi N et al. A new approach to the diagnosis of Superficial Inflammatory Dermatosis. Elixer International Journal. ISSN 2229-712X. www.elixirpublishers.com
  • Kaler AK et al. Evaluation Complex Fibroadenoma: A most neglected variant of Fibroadenoma. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013, June; 31(31): 1035-1038.
  • Parthiban R, Kaler AK, Shariff S, Sangeeta M. Squamous cell carcinoma arising from congenital lymphedema. SAGE Open Medical Case Reports. 2013. DOI: 10.1177/2050313X13496507. www.sagepub.co.uk/journalsPermissions.nav
  • Kaler AK, Shameem Shariff. Primary Ewing’s Sarcoma of the paranasal sinuses and orbit. Innovative Journal of Medical and Health Science 2013 Jan-Feb; 3: 1-3.
  • Kaler AK et al. HbH disease a rare but perilious variant of Alpha Thalassemia. Journal of Pharmaceutical and Biomedical Sciences (J Pharm Biomed Sci) 2013, February; 27: 543-546. www.jpbms.info
  • Shweta Prasad, Kaler AK, Shameem Shariff. Ask-Upmark Kidney: A Report of 2 cases. International Journal of Health Sciences and Research 2013; 3(1).
  • Kaler AK, Jena M, Gandhi N, Shantha B. Endometrial Stromal Sarcoma of the Uterus: A rare entity. International Journal of Health Sciences & Research. 2012; 2(6).
  • Vasudev DS, Kaler AK. Non Hodgkin’s Lymphoma of Uterine Cervix. Online J Health Allied Sciences 2012; 11(1):13.
  • Kaler A K, Shankar A, Madhusmatha J. Plasmacytoma of soft tissues and gingiva. Online J Health Allied Sciences 2012; 11(2).
  • Kaler KA. Exchange Transfusion. Sankalp Patrika. 2013 May; 3(5): 10.
  • Kaler K A. Ask the Doctor: New approach for the transfusion of patients with Thalassemia Major: Neocytopheresis. Sankalp Patrika 2011; 1 (7), 16.
  • Kaler K A. Storage and its effects on Blood and Blood Components. Sankalp Patrika 2011; 1 (8), 2.

PROFESSIONAL MEMBERSHIPS

  • Member of Karnataka Chapter - Indian Academy Pathology and Microbiology
  • Guest Editor for Journal of Precision Oncology, HCG Cancer Care Hospitals.

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