Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute - Medical Research Department (KDAH-MRD) has been constituted in the year 2009, under the able leadership of Executive Director Dr Ram Narain.
The Research Mission of KDAH-MRD is to undertake and promote excellence in clinical research and to foster and support patient care and treatment. At KDAH-MRD, Pharma-sponsored, Government- sponsored, Investigator-initiated and Academic research projects provide the foundation for the research activities. These projects are complemented by large organizational projects, population-based epidemiologic studies, community-based intervention programs, multicenter controlled clinical trials, and research training programs.
Special features of KDAH-MRD:
Experienced and GCP trained Research Investigators assisted by a dedicated and full time GCP trained Research Team.
Spacious working area with facilities for storage, audit and archival of research related activities
Updated SOPs in accordance with national and international regulations.
Research activities includes but not limited to the following main areas of particular scientific and clinical interest:
Centre for Accident & Emergency
Centre for Cancer
Centre for Children
Centre for Diabetes and Obesity
Centre for Neurosciences
Centre for Transplant
Centre for Bone and Joint
Centre for Cardiac Sciences
Children’s Heart Centre
Centre for Mother & Child
Centre for Physical Medicine & Rehabilitation
Centre for Pulmonary Medicine
Centre for Internal Medicine
Centre for Gastroenterology
The main objective of the department is to:
Set directions, priorities and thrust areas for Research.
Periodically review the progress of Scientific and Clinical Research Projects.
Suggest and review Research Proposals within KDAH and in collaborations with other National and International Organizations.
Review sponsored (Pharma Sponsored, Govt Sponsored etc.) Research Proposals for feasibility and conduct at the Institute.
Coordinate the functioning of committees for research and ethics in KDAH
Clinical studies helps to bridge research and patient care by evaluating therapies, drugs and diagnostic tools to give way to discoveries that might be of benefit to the human patients in future.
Clinical trials are used to test the safety and effectiveness of drugs and devices. Usually, they are sponsored by pharmaceutical companies and are conducted by research teams that include doctors and other medical professionals. Clinical trials are typically conducted in four phases:
- Phase I is when generally healthy people are given the medication to test if the ingestion of the pill or treatment will have no adverse and/or toxicological effect and that it is absolutely safe to be used in human patients.
- Phases II and III involves deeper evaluation regarding the safety, effectiveness, and dosage of the medication. It’s after these stages that the country drug regulator would approve the drug or device.
- Phase IV examines and conducted to collect more information for previously approved treatments.
All of the phases in clinical trials are governed by strict protocols, and are overseen by many regulatory bodies, from the Drug Controller General of India to Institutional Ethics Committee (IEC). IECs are a group of independent medical experts, ethicists, as well as lay person. Researchers periodically report to the IEC regarding entire conduct of the study which includes the tests involved in the study, the results recorded and even the side effects reported. According to the recent regulations, IEC now needs to be accreditated with NABH. (National Accreditation Board for Hospitals)
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