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Dr. Santanu Sen

Consultant in Paediatrics, Paediatric Oncology & Stem Cell Transplantation
MBBS, DCH, FRCPCH, FRCP(Edin), CCT Paediatrics(UK)

Fellowships

  • Paediatric Oncology, Royal Victoria Infirmary, Newcastle, UK
  • Stem Cell Transplantation, Newcastle General Hospital, UK
  • Paediatric Oncology, Royal Marsden Hospital, London, UK

Expertise

  • Leukaemia and Lymphoma
  • Brain tumours
  • Neuroblastoma and other Paediatric Tumours
  • Bone Marrow Transplantation

Services Offered

Paediatric Bone Marrow Transplantation – Allogeneic, Autulogous and Haploidentical Transplants done for Thallasemia, Sickle Cell Disease, Aplastic Anaemia, Relapsed Leukemia and Lymphoma, Resistant cancers, Relapsed/resistant Ewings Tumour and Neurobla, Benign haematological conditions Thallassemia, Sickle Cell Disease, Haemophilia, Idiopathic Thrombocytopenic Purpura, Anaemia and other blood disorders, Malignant conditions Leukemia, Lymphoma, Brain tumours, Bone tumours such as Ewings Tumour and Osteosarcoma, Wilms tumour and other abdominal tumours, Neuroblastoma, Rhabdomyosarcoma and other soft tissue sarcomas., Others Haemophagocytic Lympho Histiocytosis (HLH) - special interest and large experience and Langerhans Cell Histiocytosis (LCH)
  • Dr. Santanu Sen has 16 years of experience in the field of Paediatric Oncology.
  • Dr. Sen has worked in Royal Marsden Hospital in London, which is one of the world's best cancer hospitals, treating patients with leukemia, lymphoma, brain tumours and other paediatric cancers and all pediatric bone marrow transplant patients there.

KDAH Experience:

At Kokilaben Dhirubhai Ambani Hospital he has treated all cases of paediatric cancers including leukemia, lymphoma, brain and other tumours. He is the In Charge of the Paediatric Stem Cell Transplantation program which has to its credit transplanting the smallest baby in the world (transplanted for Neuroblastoma at the age of 4 months) and the youngest thallassemia transplant in India at 9 months. With tie ups with world renowned institutions such as Royal Marsden Hospital in London, Royal Victoria Infirmary in Newcastle and Karolinksa Institute in Sweden he ensures that the latest technology and therapy is available for all his patients.

Doctor'sScorecard

  • 45

    Acute Lymphocytic Leukemia

  • 14

    Acute Myeloid Leukemia

  • 35

    Brain Tumours

  • 15

    Wilms Tumours

  • 28

    Hodgkins Lymphoma

  • 25

    Non-Hodgkins Lymphoma

  • 20

    Neuroblastoma

  • 14

    Osteosarcoma

  • 18

    Ewings Sarcoma

  • Outcomes Data with International Benchmarks

    Disease International Survival Rates KDAH Survival rates
    Acute Lymphocytic Leukemia 85% 92%
    Acute Myeloid Leukemia 64% 54%
    Brain Tumours 72% 70%
    Wilms Tumours 90% 85%
    Hodgkins Lymphoma 95% 95%
    Non-Hodgkins Lymphoma 85% 90%
    Neuroblastoma 79% 70%
    Osteosarcoma 71% 85%
    Ewings Sarcoma 75% 80%

  • Examiner – Royal College of Paediatrics & Child Health, UK
  • Examiner – College of Physicians & Surgeons, Mumbai
  • West Zonal Executive Council Representative, Pediatric Hematology Oncology Chapter, Indian Academy of Paediatrics
  • Executive Council Representative, Indian Academy of Pediatrics, Mumbai Branch
  • Member, International Society of Paediatric Oncology
  • Member, Children Cancer & Leukemia Group, UK
  • Member, American Academy of Paediatrics
  • Member, American Society of Clinical Oncology

  • Amar Thakur, Mumbai

    Thanks for teaching us the difference between Fact and Faith: Fact is when any ordinary doctor diagnoses illness in a report. Faith is when good doctors like you give their patients the strength to recover.
  • Himanshu Shah

    Despite being busy he use to take time out and explain each and every possibility that could arise….I could freely ask him as many questions as I wanted, and he used to answer most of them to clear my anxiety. Doctors like him replaces the fear of illness with trust in recovery. Though I am not the right person to comment but he has good subject knowledge and during the treatment of my child he had at times taken tough and favorable decisions which were life saving for my child. His concern for illness, personal attention and professional approach was just remarkable. He has saved my child from a critical illness.
  • Adv. Mrs Ketaki Agarwal & Abhinav Agarwal.

    And we cannot imagine a paediatric ward without Dr.Santanu Sen....He surely is a good samaritan, an angel to all his infant patients...The best quality in him is his patience and he has never shown us at any point of time tantrums or attitude...or never has he given us an impression of obliging us by attending to our needs whenever we required his urgent help.
  • Devisha Jatakia

    As a patient i am highly satisfied with the treatment and care offered by Dr Sen in my tough and tide. He is a clam listener who always helps us to express our problems and silly queries. He have asked him the most lamest questions and disturbed him in the most peaceful hours of his life but never ever he have showed any disrespect or harshness. Even during times when he is busy he makes an effort to let us know that he will revert back soon...and he surely does!!
  • Kainaaz Amra

    Words fail me to describe our regard, love and faith we have for Dr. Shantanu. The way our daughters are handled by him is beyond a 'Doctor's duty'. We do not trust ANY other doctor except him to take care of our little babies, not even for simple things such as vaccinations.
  • Nivedita Mishra

    We gained confidence in your capability and the entire team’s helpfulness in our first serious emergency. We still remember the day when our 5 year old child got an attack of HSP. We were a bit late in realising that it was more than ordinary rashes and reached the hospital very confused. Your timely diagnosis was a key reason why our child Mann could manage to recover soon.
  • Sarmistha Roy

    Dr Shantanu calm, positive and outgoing demeanor has always had a calming and positive influence on our entire family. Radhika looks forward to her visit to Dr Shantanu.
  • Priya Chawla

    The diagnosis and treatment each time has been completely satisfying..Thank-you ever so much Dr. Sen!You rock!!
  • Garima Bagrecha

    He gives time, available on a call...very patient, less medicines!!
  • Ashish Agrawal

    I'll be perfectly fine my heart is rest assue for that. As a patient your doc approach would very important & as per my experience the way Dr.sen is treating patient friendly. He never let me down even though in hard to hard situations like operations/Chemo/Radiation/Therapy etc.
  • Jitesh Bhaskaran

    Your approach towards patients is so good that we could feel free to approach you over phone / sms at any time for which you have always responded, which has helped us to give proper medication without any loss of time and has led to his speedy recovery. In fact, We have no words to express our gratitude for bringing out and saving our son from such a serious and complicated surgery which can be achieved only by such a competent, well-dedicated, patient-friendly, experienced and sincere Doctor like you.
  • Henal Kisani

    We are extremely convinced and we know exactly whom to go to regarding any health issues of our daughter. We would like to thank Dr.sen and the staff at the paediatric clinic and ward of the hospital who have cared for and helped us and beautifully fulfilled their duties towards patients. We are glad and thank Dr.Santanu Sen for building and maintaining the trust that we have put in him regarding our only daughters health. We wish him all the very best for all the future endeavours.
  • Richa Sood

    Dr. Sen is one of the most humble human beings I have come across in my life. As a doctor, he is something anyone can totally trust on with closed eyes...... No matter what time of day it is, he is always there whenever needed... A person very committed to his profession....
  • Raaghav Dar

    We all have immense trust, respect and love for you as our daughter's doctor and have your loving care and professional advise to thank for her proper growth and development.
  • Father of Raizel

    Dr. Sen's approach towards children is very friendly which comforts them a lot! His room is so inviting for children with all the colourful miniatures displayed... We love it too!
Dr. Santanu Sen

Naveen(name changed for privacy of patient) was only 1 week old when his doctors told his devastated parents that he has a large tumour in his tummy.

A lot of detailed tests including ultrasonography and CT scan of his abdomen confirmed the suspicion that he has a neuroblastoma, a tumour that originates from the supra-renal gland on top of the kidneys.

Further tests and a biopsy of the tumour showed that though the tumour was limited only to the original site with no distal spread (metastasis), it was positive for ‘Myc-N’, a genetic marker which signifies that it was a very aggressive tumour that needs intensive treatment.

Chemotherapy was started from 1 month of age and he underwent 8 cycles of intensive chemotherapy over the next 3 months and at the age of 5 months had surgery to remove the tumour.

But even this was not enough as this aggressive tumour needs further high dose therapy followed by stem cell transplantation for its treatment.

The problem was that at this young age of 6 months and weighing only 6 kg, a transplant was a difficult proposition and very few institutions has the expertise for such a procedure.

The BMT team at KDAH, which has the significant experience of doing paediatric, transplant was uniquely suited for this difficult task. Dr Santanu Sen, who had extensive experience of paediatric transplants in UK said that the fact that they have a complete multidisciplinary team with full time consultants makes it a safe place for such difficult procedures.

The first major challenge was collecting the stem cells from the patient for the transplant. A special machine called a cell separator is used to centrifuge and filter out the stem cells from the blood but using it on such a small baby was challenging. This was because almost the entire child blood volume had to be cycled very rapidly and constantly through the machine. In fact the machine had to be primed (filled) with a separate blood unit from a donor prior to use as otherwise the childs own blood volume would have been inadequate to even start the machine. In fact the child blood was cycled through the machine once every 10-15 minutes for 6 hours to get enough stem cells for the transplant.

The stem cell collection was done in the Paediatric Intensive Care Unit with both the Paediatric and Neonatal Intensive Care Consultants in constant attendance to monitor the baby. In fact, the Paediatric Cardiac Intensivist was at the bedside constantly monitoring the babys heart throughout the procedure to ensure the child safety.

Successful collection of stem was done with no untoward events and a second collection was again done the next day.

This was the first time that such a procedure has been done on such a small child in India and internationally, less than five such cases has been reported in the literature.

The stem cell transplantation was successfully carried out and the child showed signs of recovery within 10 days which also is very early (usual is 14-21 days). In fact the child was discharged in a stable condition on the 18th day after the transplant which also is a record as usually it takes upto 4 weeks before a child is discharged.

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