What is Wilson Disease?
Wilson disease is a genetic disorder resulting in excessive accumulation of copper in the body. Normally, the liver excretes almost all of the ingested copper except for the minute quantities required for maintaining healthy nerves, bones, and skin. People with Wilson disease are unable to excrete copper, therefore, over a period of time copper slowly accumulates in their bodies resulting in damage to various organs.
Who needs to be tested for Wilson Disease?
Any child or young adult with the following problems needs to be evaluated for Wilson Disease:
All brothers and sisters of a person with Wilson Disease need to be tested, even if they are normal.
How is Wilson Disease diagnosed?
Wilson Disease can be diagnosed based on a careful clinical evaluation by a neurologist or hepatologist (liver doctor) familiar with the disease and specialised tests like lab test, MRI and liver biopsy.
Is Wilson Disease treatable?
YES, it is treatable. With timely diagnosis and treatment people with Wilson Disease can lead a normal life. Children return to normal education and excel. Even people with severe disability improve and resume school/work.What is the treatment for Wilson Disease?
Treatment involves avoiding food rich in copper and taking drugs to eliminate excess copper (decoppering drugs). People with symptoms as well as those who do not have any symptoms need treatment. Treatment is lifelong. It is essential that treatment be tailored to an individual patient.
Wilson's Disease clinicComplimenting the expert clinicians is the comprehensive care we offer during diagnosis of the patients for their complete rehabilitation. Wilson Disease is curable. However, today people with Wilson Disease suffer considerable disability due to delay in diagnosis and inadequate treatment.
Kokilaben Hospital is proud to introduce a comprehensive clinic that is devoted to treatment and care of people with Wilson Disease and their families. The aim of the Wilson Disease Clinic is to ensure that no person in India goes undiagnosed or untreated.
The Wilson Disease Clinic offers a comprehensive care program including neurology and liver specialist consultation, physical and cognitive rehabilitation, psychotherapy, speech therapy and gait training. Since Wilson Disease is a familial disease we also offer family counselling services, screening of siblings and genetic counselling.Laboratory
Specialised tests like serum ceruloplasmin, 24 hour urine copper and liver copper estimations are available. The hospital also offers facility of mailing-in of samples to support centres that do not have these test facilities.3 Tesla MRI
This is useful to assess the extent of brain and liver injury from excessive copper deposition.Usg guided liver Biopsy
In some people, diagnosis of Wilson disease requires a procedure called a liver biopsy, wherein, a thin needle is inserted through the skin & into the liver under ultrasound guidance (USG) and a small sample of liver tissue is drawn out. This sample is then sent to the laboratory to test for excess copper.Endoscopy Lab
This is a part of the hepatology (liver) department and provides specialised treatment for patients with severe liver failure or cirrhosis.Ophthalmology Lab
It offers comprehensive eye check including examination through microscope with high intensity light source (slit lamp) and special eye camera photography to identify copper deposits in the eye. These are useful to diagnose as well as to monitor people with Wilson Disease.Rehabilitation
Kokilaben Hospital has dedicated 30,000 sq ft of floor area equipped with cutting edge equipment to provide personalised & goal directed physiotherapy, speech therapy and gait retraining. Our specialised physical and cognitive occupational rehabilitation program ensures that patients return to normal life as soon as possible.Family support and counselling
The Wilson Disease Clinic provides extensive patient as well as caregiver support, counselling and education services. We believe that a better understanding of the disease paves way for early diagnosis, appropriate and timely treatment, improved compliance and better doctor patient interaction.Genetic counselling
Kokilaben Hospital offers genetic counselling services to patients with Wilson disease to assess risk of passing the disease to their children.Screening brothers and sisters of a person with Wilson Disease
A blood test called DNA Analysis can identify the genetic defects that cause Wilson Disease. This test is available at a limited number of medical centres and is done using a small sample of blood drawn from a person's arm or collected from a finger prick. This test can be useful in diagnosing Wilson Disease.Vaccinations
People with Wilson Disease can develop serious complications if they contact liver infection (hepatitis). To prevent likelihood of developing liver infection the Wilson Disease Clinic offers vaccination for Hepatitis A & B to all persons with Wilson Disease as well as their brothers and sisters.Mailing-in samples
Kokilaben Hospital offers the facility of mailing-in samples for serum ceruloplasmin, 24 urine copper, liver copper and genetic analysis.Packages
Kokilaben Hospital is devoted to and brings the best in medical care at convenient & affordable packages.
Package 1: Diagnosis
This package includes consultations with Wilson Disease experts (Dr. Annu Aggarwal, Dr. Mohit Bhatt and Dr. Geeta Billa) and an array of tests to confirm diagnosis of Wilson Disease in a person.
Package 2: Sisters & brothers screening
This package is designed to screen sisters & brothers of patients with Wilson Disease. It includes consultations with Dr. Annu Aggarwal and Dr. Mohit Bhatt.
Package 3: Rehabilitation
This package is designed to fine tune treatment and rehabilitate persons with Wilson Disease. It includes consultation with Dr. Annu Aggarwal and Dr. Mohit Bhatt.
Package 4: Follow up
This package is designed to monitor disease progression & treatment adequacy in patients on treatment. It includes consultation with Dr. Annu Aggarwal and Dr. Mohit Bhatt.
Milestones of the Wilson Disease Clinic
The Wilson Disease Clinic at Kokilaben Hospital is committed to support patients with Wilson Disease and their families, increase public awareness of the disease and encourage research in the field.
The clinic supports physicians and centres involved in care of patients with Wilson Disease within India as well as in the Indian subcontinent (Pakistan, Bangladesh and Sri Lanka), Australia & China.
The clinic has made important scientific contribution to the understanding of Wilson Disease and management of people with the disease, including:
The research results have been published in leading international medical & neurological journals.
Contact detailsWilson Disease Clinic